GOOGA: A platform to synthesize mapping experiments and identify genomic structural diversity.

Understanding genomic structural variation such as inversions and translocations is a key challenge in evolutionary genetics. We develop a novel statistical approach to comparative genetic mapping to detect large-scale structural mutations from low-level sequencing data. The procedure, called Genome...

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Bibliographic Details
Main Authors: Lex E Flagel, Benjamin K Blackman, Lila Fishman, Patrick J Monnahan, Andrea Sweigart, John K Kelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6483263?pdf=render