Cardioprotective Effects of VCP Modulator KUS121 in Murine and Porcine Models of Myocardial Infarction

Cardioprotective Effects of VCP Modulator KUS121 in Murine and Porcine Models of Myocardial Infarction

Summary: No effective treatment is yet available to reduce infarct size and improve clinical outcomes after acute myocardial infarction by enhancing early reperfusion therapy using primary percutaneous coronary intervention. The study showed that Kyoto University Substance 121 (KUS121) reduced endop...

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Main Authors: Yuya Ide, MD, Takahiro Horie, MD, PhD, Naritatsu Saito, MD, PhD, Shin Watanabe, MD, PhD, Chiharu Otani, MD, Yui Miyasaka, BSc, Yasuhide Kuwabara, MD, PhD, Tomohiro Nishino, MD, PhD, Tetsushi Nakao, MD, PhD, Masataka Nishiga, MD, PhD, Hitoo Nishi, MD, PhD, Yasuhiro Nakashima, MD, PhD, Fumiko Nakazeki, MD, PhD, Satoshi Koyama, MD, PhD, Masahiro Kimura, MD, Shuhei Tsuji, MD, Randolph Ruiz Rodriguez, MD, Sijia Xu, MD, Tomohiro Yamasaki, MD, Toshimitsu Watanabe, MD, Masamichi Yamamoto, PhD, Motoko Yanagita, MD, PhD, Takeshi Kimura, MD, PhD, Akira Kakizuka, MD, PhD, Koh Ono, MD, PhD
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X19301822

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http://www.sciencedirect.com/science/article/pii/S2452302X19301822

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