Therapeutic efficacy of alpha-RIT using a 213Bi-anti-hCD138 antibody in a mouse model of ovarian peritoneal carcinomatosis

Therapeutic efficacy of alpha-RIT using a 213Bi-anti-hCD138 antibody in a mouse model of ovarian peritoneal carcinomatosis

Purpose: Ovarian peritoneal carcinomatosis is a pathology for which effective cures are currently lacking. New research protocols seek to eradicate residual micrometastases following cytoreductive surgery by using Hyperthermic Intraperitoneal Chemotherapy (HIPEC), or Radioimmunotherapy (RIT). This s...

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Bibliographic Details
Main Authors: Aurélie eDerrien, Sébastien eGouard, Catherine eMaurel, Marie-Helene eGaugler, Frank eBruchertseifer, Alfred eMorgenstern, Alain eFaivre-Chauvet, Jean-Marc eClasse, Michel eChérel
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Medicine
Subjects:
Radioimmunotherapy
HIPEC
CD138
alpha-particles
ovarian peritoneal carcinomatosis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00088/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00088/full

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