Immortalization and Characterization of Porcine Macrophages That Had Been Transduced with Lentiviral Vectors Encoding the SV40 Large T Antigen and Porcine Telomerase Reverse Transcriptase

The domestic pig is an important agricultural animal, and thus, infectious diseases that affect pigs can cause severe economic losses in the global swine industry. Various porcine pathogens target macrophages, which are classical innate immune cells. Although macrophages basically protect the host f...

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Bibliographic Details
Main Authors: Takato Takenouchi, Hiroshi Kitani, Shunichi Suzuki, Michiko Nakai, Dai-ichiro Fuchimoto, Mitsutoshi Tsukimoto, Hiroki Shinkai, Mitsuru Sato, Hirohide Uenishi
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Veterinary Science
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fvets.2017.00132/full