Molecular markers associated with the outcome of tamoxifen treatment in estrogen receptor-positive breast cancer patients: scoping review and in silico analysis

Molecular markers associated with the outcome of tamoxifen treatment in estrogen receptor-positive breast cancer patients: scoping review and in silico analysis

Abstract Tamoxifen (TMX) is used as adjuvant therapy for estrogen receptor-positive (ER+) breast cancer cases due to its affinity and inhibitory effects. However, about 30% of cases show drug resistance, resulting in recurrence and metastasis, the leading causes of death. A literature review can hel...

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Bibliographic Details
Main Authors: Maiquidieli Dal Berto, Giovana Tavares dos Santos, Aniúsca Vieira dos Santos, Andrew Oliveira Silva, José Eduardo Vargas, Rafael José Vargas Alves, Fernanda Barbisan, Ivana Beatrice Mânica da Cruz, Claudia Giuliano Bica
Format: Article
Language:English
Published: Springer 2021-10-01
Series:Discover Oncology
Subjects:
Recurrence
Tamoxifen
Breast cancer
HR positive
Biological processes
Molecular targets
Online Access:https://doi.org/10.1007/s12672-021-00432-7

Internet

https://doi.org/10.1007/s12672-021-00432-7

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