Stereological Investigation of Regional Brain Volumes after Acute and Chronic Cuprizone-Induced Demyelination

Stereological Investigation of Regional Brain Volumes after Acute and Chronic Cuprizone-Induced Demyelination

Brain volume measurement is one of the most frequently used biomarkers to establish neuroprotective effects during pre-clinical multiple sclerosis (MS) studies. Furthermore, whole-brain atrophy estimates in MS correlate more robustly with clinical disability than traditional, lesion-based metrics. H...

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Bibliographic Details
Main Authors: Tanja Hochstrasser, Sebastian Rühling, Kerstin Hecher, Kai H. Fabisch, Uta Chrzanowski, Matthias Brendel, Florian Eckenweber, Christian Sacher, Christoph Schmitz, Markus Kipp
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
multiple sclerosis
cuprizone
atrophy
design-based stereology
18F-FDG
Online Access:https://www.mdpi.com/2073-4409/8/9/1024

Internet

https://www.mdpi.com/2073-4409/8/9/1024

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