Inhibitors of Chemoresistance Pathways in Combination with Ara-C to Overcome Multidrug Resistance in AML. A Mini Review

Inhibitors of Chemoresistance Pathways in Combination with Ara-C to Overcome Multidrug Resistance in AML. A Mini Review

Acute myeloid leukemia (AML), the most common type of leukemia in older adults, is a heterogeneous disease that originates from the clonal expansion of undifferentiated hematopoietic progenitor cells. These cells present a remarkable variety of genes and proteins with altered expression and function...

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Bibliographic Details
Main Authors: Guadalupe Rosario Fajardo-Orduña, Edgar Ledesma-Martínez, Itzen Aguiñiga-Sánchez, María de Lourdes Mora-García, Benny Weiss-Steider, Edelmiro Santiago-Osorio
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
leukemia
relapse
refractory disease
drug resistance
overcoming chemoresistance
Online Access:https://www.mdpi.com/1422-0067/22/9/4955

Internet

https://www.mdpi.com/1422-0067/22/9/4955

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