Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer

Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer

Abstract Background Prognostic tools for prostate cancer (PC) are inadequate and new molecular biomarkers may improve risk stratification. The epigenetic mark 5-hydroxymethylcytosine (5hmC) has recently been proposed as a novel candidate prognostic biomarker in several malignancies including PC. 5hm...

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Bibliographic Details
Main Authors: Tine Maj Storebjerg, Siri H. Strand, Søren Høyer, Anne-Sofie Lynnerup, Michael Borre, Torben F. Ørntoft, Karina D. Sørensen
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Clinical Epigenetics
Subjects:
Prostate cancer
Prognosis
Biomarker
Epigenetics
Immunohistochemistry
5-methylcytosine
Online Access:http://link.springer.com/article/10.1186/s13148-018-0540-x

Internet

http://link.springer.com/article/10.1186/s13148-018-0540-x

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