α-bisabolol is an effective proapoptotic agent against BCR-ABL(+) cells in synergism with Imatinib and Nilotinib.

α-bisabolol is an effective proapoptotic agent against BCR-ABL(+) cells in synergism with Imatinib and Nilotinib.

We showed that α-bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias (ALL). Here we studied the activity of α-bisabolol against BCR-ABL(+) cells using 3 cell lines (K562, LAMA-84, CML-T1) and 10 primary BCR-ABL(+) ALL samples. We found that: (...

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Bibliographic Details
Main Authors: Massimiliano Bonifacio, Antonella Rigo, Emanuele Guardalben, Christian Bergamini, Elisabetta Cavalieri, Romana Fato, Giovanni Pizzolo, Hisanori Suzuki, Fabrizio Vinante
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3463553?pdf=render

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http://europepmc.org/articles/PMC3463553?pdf=render

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