Immune checkpoint molecule expression is altered in the skin and peripheral blood in vasculitis

Abstract Dysfunction of immunoinhibitory signals and persistent T cell activation reportedly play important roles in the development of vasculitis. The skin is one of the most accessible organs, and it is suitable for the characterization of immune cell signatures. However, the inhibitory checkpoint...

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Bibliographic Details
Main Authors: Chie Miyabe, Yupeng Dong, Takaharu Ikeda, Kazuo Takahashi, Yoshishige Miyabe, Tamihiro Kawakami
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-99558-5