South African Abietane Diterpenoids and Their Analogs as Potential Antimalarials: Novel Insights from Hybrid Computational Approaches

The hemoglobin degradation process in <i>Plasmodium</i> parasites is vital for nutrient acquisition required for their growth and proliferation. In <i>P. falciparum</i>, falcipains (FP-2 and FP-3) are the major hemoglobinases, and remain attractive antimalarial drug targets....

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Bibliographic Details
Main Authors: Thommas Musyoka, Özlem Tastan Bishop
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/22/4036