Role of Saccharomyces single-stranded DNA-binding protein RPA in the strand invasion step of double-strand break repair.
The single-stranded DNA (ssDNA)-binding protein replication protein A (RPA) is essential for both DNA replication and recombination. Chromatin immunoprecipitation techniques were used to visualize the kinetics and extent of RPA binding following induction of a double-strand break (DSB) and during it...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2004-01-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC314472?pdf=render |