Role of Saccharomyces single-stranded DNA-binding protein RPA in the strand invasion step of double-strand break repair.

The single-stranded DNA (ssDNA)-binding protein replication protein A (RPA) is essential for both DNA replication and recombination. Chromatin immunoprecipitation techniques were used to visualize the kinetics and extent of RPA binding following induction of a double-strand break (DSB) and during it...

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Bibliographic Details
Main Authors: Xuan Wang, James E Haber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC314472?pdf=render