uPAR-controlled oncolytic adenoviruses eliminate cancer stem cells in human pancreatic tumors

Pancreatic tumors contain cancer stem cells highly resistant to chemotherapy. The identification of therapies that can eliminate this population of cells might provide with more effective treatments. In the current work we evaluated the potential of oncolytic adenoviruses to act against pancreatic c...

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Bibliographic Details
Main Authors: Luciano Sobrevals, Ana Mato-Berciano, Nerea Urtasun, Adela Mazo, Cristina Fillat
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506113001347