Integrative analysis of the gut microbiome and metabolome in a rat model with stress induced irritable bowel syndrome

Abstract Stress is one of the major causes of irritable bowel syndrome (IBS), which is well-known for perturbing the microbiome and exacerbating IBS-associated symptoms. However, changes in the gut microbiome and metabolome in response to colorectal distention (CRD), combined with restraint stress (...

Full description

Bibliographic Details
Main Authors: Yue Hu, Fang Chen, Haiyong Ye, Bin Lu
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97083-z