Exogenous activation of cannabinoid-2 receptor modulates TLR4/MMP9 expression in a spinal cord ischemia reperfusion rat model

Exogenous activation of cannabinoid-2 receptor modulates TLR4/MMP9 expression in a spinal cord ischemia reperfusion rat model

Abstract Background Cannabinoid-2 receptor (CB2R) plays an important role in the cascading inflammation following ischemic injury. The toll-like receptors 4 (TLR4)/matrix metalloproteinase 9 (MMP9) signal pathway is involved in blood-brain barrier dysfunction induced by ischemia stroke. The aim of t...

Full description

Bibliographic Details
Main Authors: Na Jing, Bo Fang, Zhe Li, Ayong Tian
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Neuroinflammation
Subjects:
Cannabinoid-2 receptor
Ischemia reperfusion
Blood-spinal cord barrier
TLR4
MMP9
Astrocyte
Online Access:http://link.springer.com/article/10.1186/s12974-020-01784-7

Internet

http://link.springer.com/article/10.1186/s12974-020-01784-7

Similar Items