Collagen Fibrillogenesis in the Mitral Valve: It’s a Matter of Compliance

Collagen fibers are essential structural components of mitral valve leaflets, their tension apparatus (chordae tendineae), and the associated papillary muscles. Excess or lack of collagen fibers in the extracellular matrix (ECM) in any of these structures can adversely affect mitral valve function....

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Bibliographic Details
Main Authors: Richard L. Goodwin, Arash Kheradvar, Russell A. Norris, Robert L. Price, Jay D. Potts
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/8/8/98