Autophagy induces G0/G1 arrest and apoptosis in menstrual blood-derived endometrial stem cells via GSK3-β/β-catenin pathway

Autophagy induces G0/G1 arrest and apoptosis in menstrual blood-derived endometrial stem cells via GSK3-β/β-catenin pathway

Abstract Background/aims Menstrual blood-derived endometrial stem cells (MenSCs) emerge as an ideal source for cell-based treatment in regenerative medicine and immunotherapy. However, the major obstacle is the low survival rate in tissues and the limited expansion number. Autophagy is an intracellu...

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Bibliographic Details
Main Authors: Jiang Du, Xinxing Zhu, Rui Guo, Zhihao Xu, Fang Fang Cheng, Qing Liu, Fen Yang, Lihong Guan, Yanli Liu, Juntang Lin
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Stem Cell Research & Therapy
Subjects:
Autophagy
Menstrual blood-derived endometrial stem cells
G0/G1 arrest
Gsk3β
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s13287-018-1073-0

Internet

http://link.springer.com/article/10.1186/s13287-018-1073-0

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