Protein topology determines cysteine oxidation fate: the case of sulfenyl amide formation among protein families.
Cysteine residues have a rich chemistry and play a critical role in the catalytic activity of a plethora of enzymes. However, cysteines are susceptible to oxidation by Reactive Oxygen and Nitrogen Species, leading to a loss of their catalytic function. Therefore, cysteine oxidation is emerging as a...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-03-01
|
| Series: | PLoS Computational Biology |
| Online Access: | http://europepmc.org/articles/PMC4351059?pdf=render |