Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain

Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain

Abstract Background Dissemination of breast cancers to the brain is associated with poor patient outcome and limited therapeutic options. In this study we sought to identify novel regulators of brain metastasis by profiling mouse mammary carcinoma cells spontaneously metastasising from the primary t...

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Bibliographic Details
Main Authors: Magdalena Kijewska, Carmen Viski, Frances Turrell, Amanda Fitzpatrick, Antoinette van Weverwijk, Qiong Gao, Marjan Iravani, Clare M. Isacke
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Breast Cancer Research
Subjects:
Breast cancer metastasis
Brain metastasis
Spontaneous metastasis
Mouse models
4T1
ID2
Online Access:http://link.springer.com/article/10.1186/s13058-018-1093-9

Internet

http://link.springer.com/article/10.1186/s13058-018-1093-9

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