Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells

Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells

Pterocephalus hookeri was used as a traditional Chinese medicine for the treatment of rheumatoid arthritis. Sweroside was a main iridoid isolated from P. hookeri. The present study aimed to investigate the anti-inflammatory effect mechanism of sweroside. In RAW264.7 cells induced by lipopolysacchari...

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Bibliographic Details
Main Authors: Rui Wang, Zhaoyue Dong, Xiaozhong Lan, Zhihua Liao, Min Chen
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
sweroside
Pterocephalus hookeri
SIRT1
NF-κB
FOXO1
inflammation
Online Access:http://www.mdpi.com/1420-3049/24/5/872

Internet

http://www.mdpi.com/1420-3049/24/5/872

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