Overcoming the limitations of locally administered oncolytic virotherapy

Abstract Adenovirus (Ad) has been most extensively evaluated gene transfer vector in clinical trials due to facile production in high viral titer, highly efficient transduction, and proven safety record. Similarly, an oncolytic Ad, which replicates selectively in cancer cells through genetic modific...

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Bibliographic Details
Main Authors: JinWoo Hong, Chae-Ok Yun
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Biomedical Engineering
Subjects:
Online Access:http://link.springer.com/article/10.1186/s42490-019-0016-x