Overcoming the limitations of locally administered oncolytic virotherapy
Abstract Adenovirus (Ad) has been most extensively evaluated gene transfer vector in clinical trials due to facile production in high viral titer, highly efficient transduction, and proven safety record. Similarly, an oncolytic Ad, which replicates selectively in cancer cells through genetic modific...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | BMC Biomedical Engineering |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s42490-019-0016-x |