MicroRNA-21 Regulates Non-Small Cell Lung Cancer Cell Invasion and Chemo-Sensitivity through SMAD7

MicroRNA-21 Regulates Non-Small Cell Lung Cancer Cell Invasion and Chemo-Sensitivity through SMAD7

Background/Aims: SMAD7 is a key inhibitor of transforming growth factor β (TGFβ) receptor signaling, which regulates the alteration of cancer cell invasiveness through epithelial-mesenchymal cell conversion. Carboplatin is a commonly used drug in the chemotherapy for non-small cell lung cancer (NSCL...

Full description

Bibliographic Details
Main Authors: Lei Lin, Hong-bin Tu, Liang Wu, Ming Liu, Ge-ning Jiang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Non-small cell lung cancer (NSCLC)
Carboplatin
SMAD7
miR-21
TGFβ receptor signaling
Cancer invasion
Online Access:http://www.karger.com/Article/FullText/445571

Internet

http://www.karger.com/Article/FullText/445571

Similar Items