The Role of AKR1B10 in Physiology and Pathophysiology

AKR1B10 is a human nicotinamide adenine dinucleotide phosphate (NADPH)-dependent reductase belonging to the aldo-keto reductase (AKR) 1B subfamily. It catalyzes the reduction of aldehydes, some ketones and quinones, and interacts with acetyl-CoA carboxylase and heat shock protein 90α. The enzyme is...

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Bibliographic Details
Main Authors: Satoshi Endo, Toshiyuki Matsunaga, Toru Nishinaka
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/6/332