Distinct tumour antigen-specific T-cell immune response profiles at different hepatocellular carcinoma stages

Distinct tumour antigen-specific T-cell immune response profiles at different hepatocellular carcinoma stages

Abstract Background Cancer-testis antigens (CTAs) and tumour-associated antigens (TAAs) are frequently expressed in hepatocellular carcinoma (HCC); however, the role of tumour-antigen-specific T cell immunity in HCC progression is poorly defined. We characterized CTA- and TAA-specific T cell respons...

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Bibliographic Details
Main Authors: Chaoran Zang, Yan Zhao, Ling Qin, Guihai Liu, Jianping Sun, Kang Li, Yanan Zhao, Shoupeng Sheng, Honghai Zhang, Ning He, Peng Zhao, Qi Wang, Xi Li, Yanchun Peng, Tao Dong, Yonghong Zhang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Cancer
Subjects:
Cancer-testis antigen
Distinction
Hepatocellular carcinoma
T cell immune response
Tumour-associated antigen
Online Access:https://doi.org/10.1186/s12885-021-08720-9

Internet

https://doi.org/10.1186/s12885-021-08720-9

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