Electrically and Ultrasonically Enhanced Transdermal Delivery of Methotrexate

Electrically and Ultrasonically Enhanced Transdermal Delivery of Methotrexate

In this study, we used sonophoresis and iontophoresis to enhance the in vitro delivery of methotrexate through human cadaver skin. Iontophoresis was applied for 60 min at a 0.4 mA/sq·cm current density, while low-frequency sonophoresis was applied at a 20 kHz frequency (2 min application,...

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Bibliographic Details
Main Authors: Hiep X. Nguyen, Ajay K. Banga
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Pharmaceutics
Subjects:
iontophoresis
sonophoresis
characterization
methotrexate
transdermal delivery
Online Access:http://www.mdpi.com/1999-4923/10/3/117

Internet

http://www.mdpi.com/1999-4923/10/3/117

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