Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura.

Approximately 40% of patients who survive acute episodes of thrombotic thrombocytopenic purpura (TTP) associated with severe acquired ADAMTS13 deficiency experience one or more relapses. Risk factors for relapse other than severe ADAMTS13 deficiency and ADAMTS13 autoantibodies are unknown. ADAMTS13...

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Bibliographic Details
Main Authors: Contessa E Edgar, Deirdra R Terrell, Sara K Vesely, Jonathan D Wren, Igor M Dozmorov, Timothy B Niewold, Michael Brown, Fang Zhou, Mark Barton Frank, Joan T Merrill, Johanna A Kremer Hovinga, Bernhard Lämmle, Judith A James, James N George, A Darise Farris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4324966?pdf=render