Antiproliferative effect of D-glucuronyl C5-epimerase in human breast cancer cells

<p>Abstract</p> <p>Background</p> <p>D-glucuronyl C5-epimerase (GLCE) is one of the key enzymes in the biosynthesis of heparansulfate proteoglycans. Down-regulation of <it>GLCE </it>expression in human breast tumours suggests a possible involvement of the ge...

Full description

Bibliographic Details
Main Authors: Prudnikova Tatiana Y, Mostovich Liudmila A, Domanitskaya Natalia V, Pavlova Tatiana V, Kashuba Vladimir I, Zabarovsky Eugene R, Grigorieva Elvira V
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/10/1/27