A mechanochemical model for embryonic pattern formation: coupling tissue mechanics and morphogen expression.

Motivated by recent experimental findings, we propose a novel mechanism of embryonic pattern formation based on coupling of tissue curvature with diffusive signaling by a chemical factor. We derive a new mathematical model using energy minimization approach and show that the model generates a variet...

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Bibliographic Details
Main Authors: Moritz Mercker, Dirk Hartmann, Anna Marciniak-Czochra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3869727?pdf=render