High-frequency stimulation of the subthalamic nucleus counteracts cortical expression of major histocompatibility complex genes in a rat model of Parkinson's disease.

High-frequency stimulation of the subthalamic nucleus (STN-HFS) is widely used as therapeutic intervention in patients suffering from advanced Parkinson's disease. STN-HFS exerts a powerful modulatory effect on cortical motor control by orthodromic modulation of basal ganglia outflow and via an...

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Bibliographic Details
Main Authors: Benjamin Grieb, Gerhard Engler, Andrew Sharott, Constantin von Nicolai, Thomas Streichert, Ismini Papageorgiou, Alexander Schulte, Manfred Westphal, Katrin Lamszus, Andreas K Engel, Christian K E Moll, Wolfgang Hamel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3951430?pdf=render