Notoginsenoside R1 Reverses Abnormal Autophagy in Hippocampal Neurons of Mice With Sleep Deprivation Through Melatonin Receptor 1A

Notoginsenoside R1 Reverses Abnormal Autophagy in Hippocampal Neurons of Mice With Sleep Deprivation Through Melatonin Receptor 1A

Sleep deprivation (SD) may cause serious neural injury in the central nervous system, leading to impairment of learning and memory. Melatonin receptor 1A (MTNR1A) plays an important role in the sleep regulation upon activation by melatonin. The present study aimed to investigate if notoginsenoside R...

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Bibliographic Details
Main Authors: Yin Cao, Qinglin Li, An Zhou, Zunji Ke, Shengqi Chen, Mingrui Li, Zipeng Gong, Zhengtao Wang, Xiaojun Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
sleep deprivation
autophagy
melatonin receptor 1A
learning and memory
notoginsenoside R1
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.719313/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.719313/full

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