Producing Integrase Minus Lentivirus for Transient Expression of the Desired Protein and Reduced Side Effects of the Virus in Gene Therapy
Background: Lentiviral vectors are very efficient tools for gene therapy. But, proviral integration make their use dangerous; therefore, the safer integration deficient lentiviral vectors (IDLVs) can be produced through the use of integrase gene mutations that specifically prevent proviral integrati...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Vesnu Publications
2015-05-01
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| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/4631 |