MicroRNA-139-5p inhibits bladder cancer proliferation and self-renewal by targeting the Bmi1 oncogene

MiR-139-5p has been reported to be overexpressed in many types of cancers, but its role in bladder cancer has not been elucidated yet. Here, we report that miR-139-5p functions as a tumor suppressor in bladder cancer and inhibits the cancer stem cell self-renewal by targeting Bmi1 directly. We found...

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Bibliographic Details
Main Authors: Hongbo Luo, Rui Yang, Chun Li, Yongqing Tong, Lingling Fan, Xiuheng Liu, Chuanrui Xu
Format: Article
Language:English
Published: IOS Press 2017-07-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317718414