Repurposing Heparin as Antimalarial: Evaluation of Multiple Modifications Toward In Vivo Application

Heparin is a promising antimalarial drug due to its activity in inhibiting <i>Plasmodium</i> invasion of red blood cells and to the lack of resistance evolution by the parasite against it, but its potent anticoagulant activity is preventing the advance of heparin along the clinical pipel...

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Bibliographic Details
Main Authors: Elena Lantero, Carlos Raúl Aláez-Versón, Pilar Romero, Teresa Sierra, Xavier Fernàndez-Busquets
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/9/825