A Synthetic Curcuminoid Analog, (2<i>E</i>,6<i>E</i>)-2,6-bis(2-(trifluoromethyl)benzylidene)cyclohexanone, Ameliorates Impaired Wound Healing in Streptozotocin-Induced Diabetic Mice by Increasing miR-146a

A Synthetic Curcuminoid Analog, (2<i>E</i>,6<i>E</i>)-2,6-bis(2-(trifluoromethyl)benzylidene)cyclohexanone, Ameliorates Impaired Wound Healing in Streptozotocin-Induced Diabetic Mice by Increasing miR-146a

The impairment in diabetic wound healing represents a significant clinical problem, with no efficient targeted treatments for these wound disorders. Curcumin is well confirmed to improve diabetic wound healing, however, its low bioavailability and poor solubility severely limit its clinical applicat...

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Bibliographic Details
Main Authors: Jingjuan Huang, Jia Fu, Bing Liu, Rui Wang, Tianhui You
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
curcuminoid
synthetic analog
wound healing
mir-146a
inflammation
nf-κb
Online Access:https://www.mdpi.com/1420-3049/25/4/920

Internet

https://www.mdpi.com/1420-3049/25/4/920

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