Achyranthes bidentata polypeptides prevent apoptosis by inhibiting the glutamate current in cultured hippocampal neurons

Achyranthes bidentata polypeptides prevent apoptosis by inhibiting the glutamate current in cultured hippocampal neurons

Glutamate-induced excitotoxicity plays a critical role in the neurological impairment caused by middle cerebral artery occlusion. Achyranthes bidentata polypeptides have been shown to protect against neurological functional damage caused by middle cerebral artery occlusion, but the underlying neurop...

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Bibliographic Details
Main Authors: Rong-Lu Pan, Wen-Qing Hu, Jie Pan, Li Huang, Cheng-Cheng Luan, Hong-Mei Shen
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
achyranthes bidentata polypeptides; apoptosis; caspase-3; excitotoxicity; glutamate receptors; mitochondrial dysfunction; mitochondrial membrane potential; neuroprotection; reactive oxygen species; staurosporine
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=6;spage=1086;epage=1093;aulast=Pan

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=6;spage=1086;epage=1093;aulast=Pan

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