Folding free energies of 5'-UTRs impact post-transcriptional regulation on a genomic scale in yeast.

Using high-throughput technologies, abundances and other features of genes and proteins have been measured on a genome-wide scale in Saccharomyces cerevisiae. In contrast, secondary structure in 5'-untranslated regions (UTRs) of mRNA has only been investigated for a limited number of genes. Her...

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Bibliographic Details
Main Authors: Markus Ringnér, Morten Krogh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1309706?pdf=render