Docetaxel-Encapsulating Small-Sized Polymeric Micelles with Higher Permeability and Its Efficacy on the Orthotopic Transplantation Model of Pancreatic Ductal Adenocarcinoma

Docetaxel-Encapsulating Small-Sized Polymeric Micelles with Higher Permeability and Its Efficacy on the Orthotopic Transplantation Model of Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) elicits a dense stromal response that blocks vascular access because of pericyte coverage of vascular fenestrations. In this way, the PDAC stroma contributes to chemotherapy resistance, and the small-sized nanocarrier loaded with platinum has been adopted to a...

Full description

Bibliographic Details
Main Authors: Yunfei Li, Peiran Li, Mingji Jin, Changgao Jiang, Zhonggao Gao
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
pancreatic ductal adenocarcinoma
small-sized polymeric micelles
docetaxel
permeability
orthotopic transplantation model
Online Access:http://www.mdpi.com/1422-0067/15/12/23571

Internet

http://www.mdpi.com/1422-0067/15/12/23571

Similar Items