Intermedin facilitates hepatocellular carcinoma cell survival and invasion via ERK1/2-EGR1/DDIT3 signaling cascade

Abstract As one of the most malignant cancer types, hepatocellular carcinoma (HCC) is highly invasive and capable of metastasizing to distant organs. Intermedin (IMD), an endogenous peptide belonging to the calcitonin family, has been suggested playing important roles in cancer cell survival and inv...

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Bibliographic Details
Main Authors: Fei Xiao, Hongyu Li, Zhongxue Feng, Luping Huang, Lingmiao Kong, Min Li, Denian Wang, Fei Liu, Zhijun Zhu, Yong’gang Wei, Wei Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80066-x