Enhanced Oral Absorption of Icaritin by Using Mixed Polymeric Micelles Prepared with a Creative Acid-Base Shift Method

Enhanced Oral Absorption of Icaritin by Using Mixed Polymeric Micelles Prepared with a Creative Acid-Base Shift Method

The purpose of this study was to develop mixed polymeric micelles with high drug loading capacity to improve the oral bioavailability of icaritin with Soluplus<sup>®</sup> and Poloxamer 407 using a creative acid-base shift (ABS) method, which exhibits the advantages of exclusion of organ...

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Bibliographic Details
Main Authors: Cheng Tang, Xiaoming Chen, Hua Yao, Haiyan Yin, Xiaoping Ma, Mingji Jin, Xin Lu, Quntao Wang, Kun Meng, Qipeng Yuan
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
acid-base shift method
icaritin
polymeric micelles
oral absorption
transmembrane transport
Online Access:https://www.mdpi.com/1420-3049/26/11/3450

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https://www.mdpi.com/1420-3049/26/11/3450

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