Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop
The authors show that NDR1 promotion of STAT1 translation is an important event for IFN-dependent antiviral immune response. These data suggest that NDR1 has an important role in controlling viral infections.
Bibliographic Details
Main Authors: |
Zhiyong Liu,
Qiang Qin,
Cheng Wu,
Hui Li,
Jia’nan Shou,
Yuting Yang,
Meidi Gu,
Chunmei Ma,
Wenlong Lin,
Yan Zou,
Yuanyuan Zhang,
Feng Ma,
Jihong Sun,
Xiaojian Wang |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2018-07-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-018-05176-7
|