Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop

Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop

The authors show that NDR1 promotion of STAT1 translation is an important event for IFN-dependent antiviral immune response. These data suggest that NDR1 has an important role in controlling viral infections.

Bibliographic Details
Main Authors: Zhiyong Liu, Qiang Qin, Cheng Wu, Hui Li, Jia’nan Shou, Yuting Yang, Meidi Gu, Chunmei Ma, Wenlong Lin, Yan Zou, Yuanyuan Zhang, Feng Ma, Jihong Sun, Xiaojian Wang
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05176-7

Internet

https://doi.org/10.1038/s41467-018-05176-7

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