The biogenesis and biological function of PIWI-interacting RNA in cancer

Abstract Small non-coding RNAs (ncRNAs) are vital regulators of biological activities, and aberrant levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI-interacting RNAs (piRNAs) are a novel type of small ncRNA initially discovered in germ cells that have a specific len...

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Bibliographic Details
Main Authors: Silu Chen, Shuai Ben, Junyi Xin, Shuwei Li, Rui Zheng, Hao Wang, Lulu Fan, Mulong Du, Zhengdong Zhang, Meilin Wang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13045-021-01104-3