Slounase, a Batroxobin Containing Activated Factor X Effectively Enhances Hemostatic Clot Formation and Reducing Bleeding in Hypocoagulant Conditions in Mice

Uncontrolled bleeding associated with trauma and surgery is the leading cause of preventable death. Batroxobin, a snake venom-derived thrombin-like serine protease, has been shown to clot fibrinogen by cleaving fibrinopeptide A in a manner distinctly different from thrombin, even in the presence of...

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Bibliographic Details
Main Authors: Reheman Adili MD, Madeline Jackson BS, Livia Stanger BA, Xiangrong Dai MA, Mandy Li PhD, Benjamin Xiaoyi Li PhD, Michael Holinstat PhD
Format: Article
Language:English
Published: SAGE Publishing 2021-05-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296211018510