Interleukin-6 and interleukin-6 receptor secretion by chronic lymphatic leukaemia and normal B lymphocytes: effect of PMA and PWM

Interleukin-6 (IL-6) and soluble interleukin-6 receptor (sIL-6R) were detected in supernatants of cultures of B chronic lymphatic leukaemia (CLL) lymphocytes. Phorbol-12-myristate 13 acetate (PMA) caused a decrease in the levels of IL-6 in 14 out of 16 cultures and an increase in levels of sIL6R in...

Full description

Bibliographic Details
Main Authors: I. Drucker, A. Klajman, M. Revel, Y. Manor, S. Ben-Efraim, D. Novick
Format: Article
Language:English
Published: Hindawi Limited 1997-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629359791857