Enhanced bioavailability and relative distribution of free (unconjugated) curcuminoids following the oral administration of a food-grade formulation with fenugreek dietary fibre: A randomised double-blind crossover study

Enhanced bioavailability and relative distribution of free (unconjugated) curcuminoids following the oral administration of a food-grade formulation with fenugreek dietary fibre: A randomised double-blind crossover study

Despite the various reports on enhanced bioavailable formulations of curcumin, systemic oral bioavailability of unconjugated curcuminoids remains a challenge. Considering the differences in plasma bioactivity and membrane permeability of free curcuminoids over conjugated metabolites, herein we repor...

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Bibliographic Details
Main Authors: Dinesh Kumar, Della Jacob, Subash PS, Abhilash Maliakkal, Johannah NM, Ramadassan Kuttan, Balu Maliakel, Veera Konda, Krishnakumar IM
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Functional Foods
Subjects:
Curcumin
Curcuminglucuronide
Conjugated curcumin metabolites
Bioavailability
Pharmacokinetics
Oral administration
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616000426

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