Compensation by tumor suppressor genes during retinal development in mice and humans

<p>Abstract</p> <p>Background</p> <p>The <it>RB1 </it>gene was the first tumor suppressor gene cloned from humans by studying genetic lesions in families with retinoblastoma. Children who inherit one defective copy of the <it>RB1 </it>gene have a...

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Bibliographic Details
Main Authors: Johnson Dianna, Martins Rodrigo, Schweers Brett, Donovan Stacy L, Dyer Michael A
Format: Article
Language:English
Published: BMC 2006-05-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/4/14