Crosstalk between Mitochondrial Ca2+ Uptake and Autophagy in Skeletal Muscle

Autophagy is responsible for the maintenance of skeletal muscle homeostasis, thanks to the removal of aberrant and dysfunctional macromolecules and organelles. During fasting, increased autophagy ensures the maintenance of the amino acid pool required for energy production. The activity of the mitoc...

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Bibliographic Details
Main Authors: Gaia Gherardi, Giulia Di Marco, Rosario Rizzuto, Cristina Mammucari
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/1845321