Formulation and evaluation of docetaxel nanosuspensions: In-vitro evaluation and cytotoxicity

Objective: The aim of the present study was to formulate the anticancer drug; docetaxel (DOX) as nanoparticles to enhance its biological activity. Methodology: Solvent precipitation method was used to prepare DOX-loaded nanoparticles and was stabilized by different concentrations of hydroxypropyl me...

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Bibliographic Details
Main Authors: Mohamed A. Ibrahim, Gamal A. Shazly, Fadilah S. Aleanizy, Fulwah Y. Alqahtani, Gehan M. Elosaily
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016418301592