Increased Dysfunctional and Plastic Regulatory T Cells in Idiopathic Orbital Inflammation

Increased Dysfunctional and Plastic Regulatory T Cells in Idiopathic Orbital Inflammation

BackgroundIdiopathic orbital inflammation (IOI) is a disfiguring and vision-threatening fibroinflammatory disorder. The pathogenesis of IOI has not been elucidated. We sought to clarify the regulatory T cell (Treg) distribution and function in patients with IOI.MethodsThe frequency, phenotype and fu...

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Bibliographic Details
Main Authors: Jingqiao Chen, Huijing Ye, Wei Xiao, Yuxiang Mao, Siming Ai, Rongxin Chen, Xiufen Lian, Lu Shi, Xing Wang, Shaowei Bi, Shenglan Yang, Xian Ji, Te Zhang, Huasheng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
regulatory T cell
dysfunction
plasticity
interleukin-33
idiopathic orbital inflammation
IgG4-related disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.634847/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.634847/full

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