The apoptotic response in HCT116<sup><it>BAX-/- </it></sup>cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein
<p>Abstract</p> <p>Background</p> <p>Many chemotherapeutic agents promote tumor cell death by activating the intrinsic pathway of apoptosis. Intrinsic apoptosis involves permeabilization of the mitochondrial outer membrane and the release of cytochrome c, a process that...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-10-01
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| Series: | BMC Cancer |
| Online Access: | http://www.biomedcentral.com/1471-2407/10/554 |